Sanguinarine reductase, a key enzyme of benzophenanthridine detoxification
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چکیده
منابع مشابه
Antiproliferative and antiangiogenic effects of the benzophenanthridine alkaloid sanguinarine in melanoma.
This study was aimed at evaluating the potential application of benzophenanthridine alkaloids, sanguinarine and cheleritrine, in the therapy of melanoma cancer. In vitro antiproliferative activity of sanguinarine was higher than that of cheleritrine against the B16 melanoma 4A5 cells. Both agents were able to produce DNA breaks, and the DNA unwinding assay showed that they act as DNA intercalat...
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متن کاملCorrection: Thioredoxin Glutathione Reductase from Schistosoma mansoni: An Essential Parasite Enzyme and a Key Drug Target
In the supporting information section of this paper, the structures of oltipraz and safranin in Figure S1 were incorrect. The corrected fi gure may be found at Copyright: © 2007 Kuntz et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original au...
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ژورنال
عنوان ژورنال: Plant, Cell and Environment
سال: 2006
ISSN: 0140-7791,1365-3040
DOI: 10.1111/j.1365-3040.2005.01421.x